Gene
mad1l1
- ID
- ZDB-GENE-040426-1081
- Name
- mitotic arrest deficient 1 like 1
- Symbol
- mad1l1 Nomenclature History
- Previous Names
-
- zgc:56571 (1)
- Type
- protein_coding_gene
- Location
- Chr: 1 Mapping Details/Browsers
- Description
- Predicted to be involved in attachment of mitotic spindle microtubules to kinetochore and mitotic spindle assembly checkpoint. Predicted to localize to kinetochore; mitotic spindle; and nuclear envelope. Human ortholog(s) of this gene implicated in lymphoma and prostate cancer. Orthologous to human MAD1L1 (mitotic arrest deficient 1 like 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:56571 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Thyme et al., 2019
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| mosaic variegated aneuploidy syndrome 7 with inflammation and tumor predisposition | Alliance | Mosaic variegated aneuploidy syndrome 7 with inflammation and tumor predisposition | 620189 |
| prostate cancer | Alliance | Prostate cancer, somatic | 176807 |
| Lymphoma, B-cell, somatic |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Family | IPR008672 | Spindle assembly checkpoint component Mad1 |
Domain Details Per Protein
| Protein | Length | Spindle assembly checkpoint component Mad1 |
|---|---|---|
|
UniProtKB:D9IWE2
|
717 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
mad1l1-202
(1)
|
Ensembl | 4,042 nt | ||
| ncRNA |
mad1l1-002
(1)
|
Ensembl | 508 nt |
Interactions and Pathways
No data available
Plasmids
No data available